Robert De Niro Don Lino (voice)
Martin Scorsese Sykes (voice)
Will Smith Oscar (voice)
Renée Zellweger Angie (voice)
Jack Black Lenny (voice)
Ziggy Marley Ernie (voice)
Doug E. Doug Bernie (voice)
Shelley Morrison Mrs. Sanchez (voice)
David Soren Shrimp (voice)
David P. Smith Crazy Joe (voice)